Two potential therapeutic antibodies bind to a peptide segment of membrane-bound IgE in different conformations-Reference-Cited by-同舟云学术

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Two potential therapeutic antibodies bind to a peptide segment of membrane-bound IgE in different conformations

Published:2014-01-24 Issue:1 Volume:5 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Chu Hsing-Mao,Wright Jon,Chan Yueh-Hsuan,Lin Chien-Jen,Chang Tse Wen,Lim Carmay

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms4139.pdf

Reference53 articles.

1. Chang, T. W. The pharmacological basis of anti-IgE therapy. Nat. Biotechnol. 18, 157–162 (2000).

2. Chang, T. W., Wu, P. C., Hsu, C. L. & Hung, A. F. Anti-IgE antibodies for the treatment of IgE-mediated allergic diseases. Adv. Immunol. 93, 63–119 (2007).

3. Holgate, S. T., Djukanovic, R., Casale, T. & Bousquet, J. Anti-immunoglobulin E treatment with omalizumab in allergic diseases: an update on anti-inflammatory activity and clinical efficacy. Clin. Exp. Allergy 35, 408–416 (2005).

4. Busse, W. W. et al. Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children. N. Engl. J. Med. 364, 1005–1015 (2011).

5. Kopp, M. V. et al. Omalizumab (Xolair) in children with seasonal allergic rhinitis: leukotriene release as a potential in vitro parameter to monitor therapeutic effects. Pediatr. Allergy Immunol. 18, 523–527 (2007).

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