Polyubiquitin chain-induced p62 phase separation drives autophagic cargo segregation
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/s41422-018-0017-7.pdf
Reference29 articles.
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3. Rea, S. L., Walsh, J. P., Layfield, R., Ratajczak, T. & Xu, J. New insights into the role of sequestosome 1/p62 mutant proteins in the pathogenesis of Paget’s disease of bone. Endocr. Rev. 34, 501–524 (2013).
4. Khaminets, A., Behl, C. & Dikic, I. Ubiquitin-dependent and independent signals in selective autophagy. Trends Cell. Biol. 26, 6–16 (2016).
5. Bjorkoy, G. et al. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J. Cell. Biol. 171, 603–614 (2005).
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