Trefoil factors: initiators of mucosal healing
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Molecular Biology
Link
http://www.nature.com/articles/nrm1203.pdf
Reference142 articles.
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3. Nusrat, A. et al. Hepatocyte growth factor/scatter factor effects on epithelia. Regulation of intercellular junctions in transformed and nontransformed cell lines, basolateral polarisation of c-met receptor in transformed and natural intestinal epithelia, and induction of rapid wound repair in a transformed model epithelium. J. Clin. Invest. 93, 2056–2065 (1994).
4. Santos, M. F. et al. Rho proteins play a critical role in cell migration during the early phase of mucosal restitution. J. Clin. Invest. 100, 216–225 (1997).
5. Thim, L. A new family of growth-factor-like peptides. 'Trefoil' disulphide loop structures as a common feature in breast cancer associated peptide (pS2), pancreatic spasmolytic polypeptide (PSP), and frog skin peptides (spasmolysins). FEBS Lett. 250, 85–90 (1989). In this paper, Thim first identified the structural homologies between TFF1 and TFF2 (and the Xenopus spasmolysins), and put forward the hypothesis (since largely proven to be correct) that the trefoil domain was essential for resistance to the gut milieu and for function.
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