Polymerizable Fab′ antibody fragments for targeting of anticancer drugs

Author:

Lu Zheng-Rong,Kopečková Pavla,Kopeček Jindřich

Publisher

Springer Science and Business Media LLC

Subject

Biomedical Engineering,Molecular Medicine,Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Reference22 articles.

1. Putnam, D. & Kopecek, J. Polymer conjugates with anticancer activity. Adv. Polym. Sci. 122, 55– 123 (1995).

2. Maeda, H., Seymour, L.M. & Miyamoto, Y. Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutics in vitro. Bioconjugate Chem . 3, 351–362 (1992).

3. Vasey, P.A. et al. Phase I clinical and pharmacokinetic study of PK1 [N-(2-hydroxypropyl)methacrylamide copolymer doxorubicin]: first member of a new class of chemotherapeutic agents—drug–polymer conjugates. Clin. Cancer Res. 5, 83– 94 (1999).

4. Caiolfa, V.R. et al. Novel perspectives in topoiosmerase-I inhibitor-based chemotherapy of solid tumors: MAG-camptothecin conjugates. Abstr. Ninth Intl. Symp. Recent Adv. Drug Delivery Systems. Salt Lake City, UT, February 22, 1999, p. 46.

5. Fritzberg, A.R. Biorecognition of antibodies in vivo: potential in drug targeting. J. Mol. Recognition 9, 309–315 (1996).

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