Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology
Link
http://www.nature.com/articles/ncb0301_245.pdf
Reference31 articles.
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2. Slamon, D. J. et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244, 707–712 (1989).
3. Yu, D. & Hung, M-C. in DNA Alterations in Cancer (ed. Ehrlich, M.) Ch. 21 (Natick, Massachusetts, 2000).
4. Zhou, B. P. et al. HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kB pathways. J. Biol. Chem. 275, 8027–8031 (2000).
5. Downward, J. Mechanisms and consequences of activation of protein kinase B/Akt. Curr. Opin. Cell Biol. 10, 262–267 (1998).
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