Ruxolitinib
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd3652.pdf
Reference9 articles.
1. Vannucchi, A. M. et al. Advances in understanding and management of myeloproliferative neoplasms. CA Cancer J. Clin. 59, 171–191 (2009).
2. Quintás-Cardama, A. et al. Janus kinase inhibitors for the treatment of myeloproliferative neoplasias and beyond. Nature Rev. Drug Discov. 10, 127–140 (2011).
3. Quintás-Cardama, A. et al. Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms. Blood 115, 3109–3117 (2010).
4. US Food and Drug Administration. FDA labeling information — Jakafi. FDA website [online] , (2011).
5. Verstovsek, S. et al. Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis. N. Engl. J. Med. 363, 1117–1127 (2010).
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