A paradigm for drug discovery using a conformation from the crystal structure of a presentation scaffold-Reference-Cited by-同舟云学术

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A paradigm for drug discovery using a conformation from the crystal structure of a presentation scaffold

Published:1995-12 Issue:12 Volume:2 Page:1131-1137
ISSN:1545-9993
Container-title:Nature Structural & Molecular Biology
language:en
Short-container-title:Nat Struct Mol Biol

Author:

Zhao Baoguang,Helms Larry R.,DesJarlais Renee L.,Abdel-Meguid Sherin S.,Wetzel Ronald

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Structural Biology

Link

http://www.nature.com/articles/nsb1295-1131.pdf

Reference52 articles.

1. In vitro selection from protein and peptide libraries

2. Learning from the immune system: laboratory methods for creating and refining molecular diversity in polypeptides

3. Discovering peptide ligands using epitope libraries

4. Identification of novel peptide antagonists for GPIIb/IIIa from a conformationally constrained phage peptide library

5. Functional validation of ligand mimicry by anti-receptor antibodies: structural and therapeutic implications

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1. Thiazolidinediones: An In–Depth Study of Their Synthesis and Application to Medicinal Chemistry in the Treatment of Diabetes Mellitus;ChemMedChem;2021-05-04

2. Molecular Dynamics Simulations of Certain RGD-Based Peptides from Kistrin Provide Insight into the Higher Activity of REI-RGD34 Protein at Higher Temperature;Chemical Biology & Drug Design;2014-03-14

3. Cystine-knot peptides engineered with specificities for αIIbβ3 or αIIbβ3 and αvβ3 integrins are potent inhibitors of platelet aggregation;Journal of Molecular Recognition;2010-05-05

4. Integrins;Gene Family Targeted Molecular Design;2008-07-11

5. PIN-bodies: A new class of antibody-like proteins with CD4 specificity derived from the protein inhibitor of neuronal nitric oxide synthase;Biochemical and Biophysical Research Communications;2006-04

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