Mdmx promotes genomic instability independent of p53 and Mdm2
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc201427.pdf
Reference55 articles.
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2. Rayburn E, Zhang R, He J, Wang H . MDM2 and human malignancies: expression, clinical pathology, prognostic markers, and implications for chemotherapy. Curr Cancer Drug Targets 2005; 5: 27–41.
3. Wade M, Li YC, Wahl GM . MDM2 MDMX and p53 in oncogenesis and cancer therapy. Nat Rev Cancer 2013; 13: 83–96.
4. Lundgren K, Montes de Oca Luna R, McNeill YB, Emerick EP, Spencer B, Barfield CR et al. Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53. Genes Dev 1997; 11: 714–725.
5. Alt JR, Bouska A, Fernandez MR, Cerny RL, Xiao H, Eischen CM . Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair. J Biol Chem 2005; 280: 18771–18781.
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