PKA signaling drives mammary tumorigenesis through Src-Reference-Cited by-同舟云学术

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PKA signaling drives mammary tumorigenesis through Src

Published:2014-03-24 Issue:9 Volume:34 Page:1160-1173
ISSN:0950-9232
Container-title:Oncogene
language:en
Short-container-title:Oncogene

Author:

Beristain A G,Molyneux S D,Joshi P A,Pomroy N C,Di Grappa M A,Chang M C,Kirschner L S,Privé G G,Pujana M A,Khokha R

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Link

http://www.nature.com/articles/onc201441.pdf

Reference48 articles.

1. Nadella KS, Jones GN, Trimboli A, Stratakis CA, Leone G, Kirschner LS . Targeted deletion of Prkar1a reveals a role for protein kinase A in mesenchymal-to-epithelial transition. Cancer Res 2008; 68: 2671–2677.

2. Tharakan R, Lepont P, Singleton D, Kumar R, Khan S . Phosphorylation of estrogen receptor alpha, serine residue 305 enhances activity. Mol Cell Endocrinol 2008; 295: 70–78.

3. Yin Z, Jones GN, Towns WH, Zhang X, Abel ED, Binkley PF et al. Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis. Circulation 2008; 117: 1414–1422.

4. Almeida MQ, Stratakis CA . How does cAMP/protein kinase A signaling lead to tumors in the adrenal cortex and other tissues? Mol Cell Endocrinol 2011; 336: 162–168.

5. Kok M, Zwart W, Holm C, Fles R, Hauptmann M, Van’t Veer LJ et al. PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer. Breast Cancer Res Treat 2011; 125: 1–12.

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