Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3

Author:

Robichaud N,del Rincon S V,Huor B,Alain T,Petruccelli L A,Hearnden J,Goncalves C,Grotegut S,Spruck C H,Furic LORCID,Larsson OORCID,Muller W J,Miller W H,Sonenberg N

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Genetics,Molecular Biology

Reference82 articles.

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3. Duncan R, Milburn SC, Hershey JW . Regulated phosphorylation and low abundance of HeLa cell initiation factor eIF-4F suggest a role in translational control. Heat shock effects on eIF-4F. J Biol Chem 1987; 262: 380–388.

4. Pause A, Belsham GJ, Gingras AC, Donze O, Lin TA, Lawrence JC Jr. et al. Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function. Nature 1994; 371: 762–767.

5. Poulin F, Gingras AC, Olsen H, Chevalier S, Sonenberg N . 4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family. J Biol Chem 1998; 273: 14002–14007.

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