The polyomavirus middle T-antigen oncogene activates the Hippo pathway tumor suppressor Lats in a Src-dependent manner
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc2014347.pdf
Reference40 articles.
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3. Fluck MM, Schaffhausen BS . Lessons in signaling and tumorigenesis from polyomavirus middle T antigen. Microbiol Mol Biol Rev 2009; 73: 542–563.
4. Treisman R, Novak U, Favaloro J, Kamen R . Transformation of rat cells by an altered polyoma virus genome expressing only the middle-T protein. Nature 1981; 292: 595–600.
5. Guy CT, Cardiff RD, Muller WJ . Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Mol Cell Biol 1992; 12: 954–961.
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