The Parkinson’s gene PINK1 regulates cell cycle progression and promotes cancer-associated phenotypes
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Genetics,Molecular Biology
Link
http://www.nature.com/articles/onc201481.pdf
Reference70 articles.
1. Unoki M, Nakamura Y . Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway. Oncogene 2001; 20: 4457–4465.
2. Valente EM, Abou-Sleiman PM, Caputo V, Muqit MMK, Harvey K, Gispert S et al. Hereditary early-onset Parkinson’s disease caused by mutations in PINK1. Science 2004; 304: 1158–1160.
3. Dodson MW, Guo M . Pink1, Parkin, DJ-1 and mitochondrial dysfunction in Parkinson’s disease. Curr Opin Neurobiol 2007; 17: 331–337.
4. Gispert S, Ricciardi F, Kurz A, Azizov M, Hoepken H-H, Becker D et al. Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration. PloS One 2009; 4: e5777.
5. Haque ME, Thomas KJ, D’Souza C, Callaghan S, Kitada T, Slack RS et al. Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP. Proc Natl Acad Sci USA 2008; 105: 1716–1721.
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