Discontinuing methotrexate to enhance vaccine response
Author:
Publisher
Springer Science and Business Media LLC
Subject
Rheumatology
Link
https://www.nature.com/articles/s41584-022-00817-0.pdf
Reference10 articles.
1. Haberman, R. H. et al. Methotrexate hampers immunogenicity to BNT162b2 mRNA COVID-19 vaccine in immune-mediated inflammatory disease. Ann. Rheum. Dis. 80, 1339–1344 (2021).
2. Boekel, L. et al. Antibody development after COVID-19 vaccination in patients with autoimmune diseases in the Netherlands: a substudy of data from two prospective cohort studies. Lancet Rheumatol. 11, e778–e788 (2021).
3. Arumahandi de Silva, A. N. et al. Pausing methotrexate improves immunogenicity of COVID-19 vaccination in elderly patients with rheumatic diseases. Ann. Rheum. Dis. 81, 881–888 (2022).
4. Park, J. K. et al. Impact of temporary methotrexate discontinuation for 2 weeks on immunogenicity of seasonal influenza vaccination in patients with rheumatoid arthritis: a randomised clinical trial. Ann. Rheum. Dis. 77, 898–904 (2018).
5. Park, J. K. et al. Effect of methotrexate discontinuation on efficacy of seasonal influenza vaccination in patients with rheumatoid arthritis: a randomised clinical trial. Ann. Rheum. Dis. 76, 1559–1565 (2017).
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