Mouse models for human hyperuricaemia: a critical review
Author:
Publisher
Springer Science and Business Media LLC
Subject
Rheumatology
Link
http://www.nature.com/articles/s41584-019-0222-x.pdf
Reference127 articles.
1. Dalbeth, N., Merriman, T. R. & Stamp, L. K. Gout. Lancet 388, 2039–2052 (2016).
2. Ichida, K. et al. Decreased extra-renal urate excretion is a common cause of hyperuricemia. Nat. Commun. 3, 764 (2012). The investigators in this study generate Abcg2 -knockout mice that have increased urate concentrations and reduced gut excretion of urate. The renal excretion of urate is increased in these mice owing to overload of renal urate-handling machinery.
3. Dalbeth N. et al. Relationship between serum urate concentration and clinically evidence incident gout: an individual participant data analysis. Ann. Rheum. Dis. 77, 1048–1052 (2018).
4. Bhole, V., Choi, J. W., Kim, S. W., de Vera, M. & Choi, H. Serum uric acid levels and the risk of type 2 diabetes: a prospective study. Am. J. Med. 123, 957–961 (2010).
5. Borghi, C. et al. Serum uric acid and the risk of cardiovascular and renal disease. J. Hypertension 33, 1729–1741 (2015).
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