Revisiting unexploited antibiotics in search of new antibacterial drug candidates: the case of MSD-819 (6-chloro-2-quinoxalinecarboxylic acid 1,4-dioxide)
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology
Link
http://www.nature.com/articles/ja2016140.pdf
Reference18 articles.
1. O'Neill, J. Antimicrobial resistance: tackling a crisis for the health and wealth of nations. Rev. Antimicrob. Resist. (2014).
2. Talbot, G. H. et al. Bad bugs need drugs: an update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America. Clin. Infect. Dis. 42, 657–668 (2006).
3. CDC. Antibiotic resistance threats in The United States. Available at http://www.cdc.gov/drugresistance/pdf/ar-threats-2013-508.pdf (2013).
4. Silver, L. L. Challenges of antibacterial discovery. Clin. Microbiol. Rev. 24, 71–109 (2011).
5. Lewis, K. Platforms for antibiotic discovery. Nat. Rev. Drug Disc. 12, 371–387 (2013).
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