7-Chlorofolipastatin, an inhibitor of sterol O-acyltransferase, produced by marine-derived Aspergillus ungui NKH-007-Reference-Cited by-同舟云学术

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7-Chlorofolipastatin, an inhibitor of sterol O-acyltransferase, produced by marine-derived Aspergillus ungui NKH-007

Published:2016-03-16 Issue:8 Volume:69 Page:647-651
ISSN:0021-8820
Container-title:The Journal of Antibiotics
language:en
Short-container-title:J Antibiot

Author:

Uchida Ryuji,Nakajyo Kento,Kobayashi Keisuke,Ohshiro Taichi,Terahara Takeshi,Imada Chiaki,Tomoda Hiroshi

Publisher

Springer Science and Business Media LLC

Subject

Drug Discovery,Pharmacology

Link

http://www.nature.com/articles/ja201627.pdf

Reference22 articles.

1. Rudel, L. L., Lee, R. G. & Cockman, T. L. Acyl coenzyme A: cholesterol acyltransferase types 1 and 2: structure and function in atherosclerosis. Curr. Opin. Lipidol. 12, 121–127 (2001).

2. Alegret, M., Llaverias, G. & Silvestre, J. S. Acyl coenzyme A:cholesterol acyltransferase inhibitors as hypolipidemic and antiatherosclerotic drugs. Methods Find. Exp. Clin. Pharmacol. 26, 563–586 (2004).

3. Tardif, J. C. et al. Effects of the acyl coenzyme A:cholesterol acyltransferase inhibitor avasimibe on human atherosclerotic lesions. Circulation 110, 3372–3377 (2004).

4. Nissen, S. E. et al. Effect of ACAT inhibition on the progression of coronary atherosclerosis. N. Engl. J. Med. 354, 1253–1263 (2006).

5. Meuwese, M. C. et al. ACAT inhibition and progression of carotid atherosclerosis in patients with familial hypercholesterolemia: the CAPTIVATE randomized trial. JAMA 301, 1131–1139 (2009).

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