Studies at the ionizable position of cephalosporins and penicillins: hydroxamates as substitutes for the traditional carboxylate group
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology
Link
https://www.nature.com/articles/ja2016149.pdf
Reference12 articles.
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2. Varetto, L., Frere, J. M. & Ghuysen, J. M. The importance of the negative charge of β-lactam compounds for the inactivation of the active-site serine DD-peptidase of Streptomyces R61. FEBS 225, 218–222 (1987).
3. Miller, M. J., DeBons, F. E. & Loudon, G. M. The chemistry of a method for the determination of carboxyl-terminal residues in peptides. J. Org. Chem. 42, 1750–1762 (1977).
4. Brown, L. D., Zygmunt, W. A. & Stavely, H. E. Active derivatives of penicillin. App.Microbiol 17, 339–343 (1969).
5. Godfrey, J. C. (Bristol-Myers Co.) N-Hydroxypenicillinamides. US Patent 330181119670131.
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