Peripheral blood cells from children with RASopathies show enhanced spontaneous colonies growth in vitro and hyperactive RAS signaling
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Hematology
Link
http://www.nature.com/articles/bcj201552.pdf
Reference33 articles.
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2. Kratz CP, Niemeyer CM, Zenker M . An unexpected new role of mutant Ras: perturbation of human embryonic development. J Mol Med 2007; 85: 227–235.
3. Schubbert S, Shannon K, Bollag G . Hyperactive Ras in developmental disorders and cancer. Nat Rev Cancer 2007; 7: 295–308.
4. Rauen KA . The RASopathies. Annu Rev Genomics Hum Genet 2013; 14: 355–369.
5. Roberts AE, Allanson JE, Tartaglia M, Gelb BD . Noonan syndrome. Lancet 2013; 381: 333–342.
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