CRC—all about microbial products and barrier function?
Author:
Publisher
Springer Science and Business Media LLC
Subject
Gastroenterology,Hepatology
Link
http://www.nature.com/articles/nrgastro.2012.220.pdf
Reference10 articles.
1. Grivennikov, S. I. et al. Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature http://dx.doi.org/10.1038/nature11465 .
2. Frantz, A. L. et al. Targeted deletion of MyD88 in intestinal epithelial cells results in compromised antibacterial immunity associated with downregulation of polymeric immunoglobulin receptor, mucin-2, and antibacterial peptides. Mucosal Immunol. 5, 501–512 (2012).
3. Fukata, M. et al. Toll-like receptor-4 promotes the development of colitis-associated colorectal tumors. Gastroenterology 133, 1869–1881 (2007).
4. Chen, G. Y., Shaw, M. H., Redondo, G. & Nunez, G. The innate immune receptor Nod1 protects the intestine from inflammation-induced tumorigenesis. Cancer Res. 68, 10060–10067 (2008).
5. Tian, Y. et al. Differential effects of NOD2 polymorphisms on colorectal cancer risk: a meta-analysis. Int. J. Colorectal Dis. 25, 161–168 (2009).
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