Biologicals and biosimilars in IBD — the road to personalized treatment
Author:
Publisher
Springer Science and Business Media LLC
Subject
Gastroenterology,Hepatology
Link
http://www.nature.com/articles/nrgastro.2016.206.pdf
Reference10 articles.
1. Ben-Horin, S. & Chowers, Y. Loss of response to anti-TNF treatments in Crohn's disease. Aliment. Pharmacol. Ther. 33, 987–995 (2011).
2. Yarur, A. J. et al. The association of tissue anti-TNF drug levels with serological and endoscopic disease activity in inflammatory bowel disease: the ATLAS study. Gut 65, 249–255 (2016).
3. Brandse, J. F. et al. Loss of infliximab into feces is associated with lack of response to therapy in patients with severe ulcerative colitis. Gastroenterology 149, 350–355 (2015).
4. Gecse, K. B. et al. Efficacy and safety of the biosimilar infliximab CT-P13 treatment in inflammatory bowel diseases: a prospective, multicentre, nationwide cohort. J. Crohns Colitis 10, 133–140 (2016).
5. Ben-Horin, S. et al. Cross-immunogenicity: antibodies to infliximab in Remicade-treated patients with IBD similarly recognise the biosimilar Remsima. Gut 65, 1132–1138 (2016).
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