Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection-Reference-Cited by-同舟云学术

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Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infection

Published:2016-05 Issue:3 Volume:9 Page:677-688
ISSN:1933-0219
Container-title:Mucosal Immunology
language:en
Short-container-title:Mucosal Immunol

Author:

Glavan T W,Gaulke C A,Santos Rocha C,Sankaran-Walters S,Hirao L A,Raffatellu M,Jiang G,Bäumler A J,Goulart L R,Dandekar S

Publisher

Springer Science and Business Media LLC

Subject

Immunology,Immunology and Allergy

Link

http://www.nature.com/articles/mi201592.pdf

Reference50 articles.

1. Guadalupe, M. et al. Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy. J. Virol. 77, 11708–11717 (2003).

2. Moir, S., Chun, T.W. & Fauci, A.S. Pathogenic mechanisms of HIV disease. Annu. Rev. Pathol. 6, 223–248 (2011).

3. Dandekar, S., George, M.D. & Baumler, A.J. Th17 cells, HIV and the gut mucosal barrier. Curr. Opin. HIV AIDS 5, 173–178 (2010).

4. Sankaran, S. et al. Rapid onset of intestinal epithelial barrier dysfunction in primary human immunodeficiency virus infection is driven by an imbalance between immune response and mucosal repair and regeneration. J. Virol. 82, 538–545 (2008).

5. Maartens, G., Celum, C. & Lewin, S.R. HIV infection: epidemiology, pathogenesis, treatment, and prevention. Lancet 384, 258–271 (2014).

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