Spatial control of Cdc42 signalling by a GM130–RasGRF complex regulates polarity and tumorigenesis-Reference-Cited by-同舟云学术

Spatial control of Cdc42 signalling by a GM130–RasGRF complex regulates polarity and tumorigenesis

Published:2014-09-11 Issue:1 Volume:5 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Baschieri Francesco,Confalonieri Stefano,Bertalot Giovanni,Di Fiore Pier Paolo,Dietmaier Wolfgang,Leist Marcel,Crespo Piero,Macara Ian G.,Farhan Hesso

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms5839.pdf

Reference41 articles.

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2. Iden, S. et al. Tumour type-dependent function of the Par3 polarity protein in skin tumorigenesis. Cancer Cell 22, 389–403 (2012).

3. McCaffrey, Luke M., Montalbano, J., Mihai, C. & Macara, Ian G. Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis. Cancer Cell 22, 601–614 (2012).

4. Xue, B., Krishnamurthy, K., Allred, D. C. & Muthuswamy, S. K. Loss of Par3 promotes breast cancer metastasis by compromising cell–cell cohesion. Nat. Cell Biol. 15, 189–200 (2012).

5. Erickson, J. W., Zhang, C.-j., Kahn, R. A., Evans, T. & Cerione, R. A. Mammalian Cdc42 is a brefeldin a-sensitive component of the Golgi apparatus. J. Biol. Chem. 271, 26850–26854 (1996).

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