The emerging roles of N6-methyladenosine (m6A)-modified long non-coding RNAs in human cancers

Author:

Liu Jingwen,Zhao Wei,Zhang Leyu,Wang XiORCID

Abstract

AbstractN6-methyladenosine (m6A) epitranscriptional modifications widely exist in RNA, which play critical roles in RNA metabolism and biogenesis processes. Long non-coding RNAs (lncRNAs) are class of non-coding RNAs longer than 200 nucleotides without protein-coding ability. LncRNAs participate in a large number of vital biological progressions. With the great improvement of molecular biology, m6A and lncRNAs are attracting more attention from researchers and scholars. In this review, we overview the current status of m6A and lncRNAs based on the latest research, and propose some viewpoints for future research perspectives.

Funder

National Natural Science Foundation of China

Tianjin Medical University

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Cell Biology,Cellular and Molecular Neuroscience,Immunology

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