AAVrh.10 immunogenicity in mice and humans. Relevance of antibody cross-reactivity in human gene therapy
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.nature.com/articles/gt2014103.pdf
Reference32 articles.
1. Mingozzi F, High KA . Immune responses to AAV vectors: overcoming barriers to successful gene therapy. Blood 2013; 122: 23–36.
2. Calcedo R, Wilson JM . Humoral immune response to AAV. Front Immunol 2013; 4: 341.
3. Mays LE, Vandenberghe LH, Xiao R, Bell P, Nam HJ, Agbandje-McKenna M et al. Adeno-associated virus capsid structure drives CD4-dependent CD8+ T cell response to vector encoded proteins. J Immunol 2009; 182: 6051–6060.
4. Ciesielska A, Hadaczek P, Mittermeyer G, Zhou S, Wright JF, Bankiewicz KS et al. Cerebral infusion of AAV9 vector-encoding non-self proteins can elicit cell-mediated immune responses. Mol Ther 2013; 21: 158–166.
5. Samaranch L, San Sebastian W, Kells AP, Salegio EA, Heller G, Bringas JR et al. AAV9-mediated expression of a non-self protein in nonhuman primate central nervous system triggers widespread neuroinflammation driven by antigen-presenting cell transduction. Mol Ther 2014; 22: 329–337.
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