Thymidine phosphorylase is both a therapeutic and a suicide gene in a murine model of mitochondrial neurogastrointestinal encephalomyopathy-Reference-Cited by-同舟云学术

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Thymidine phosphorylase is both a therapeutic and a suicide gene in a murine model of mitochondrial neurogastrointestinal encephalomyopathy

Published:2014-05-08 Issue:7 Volume:21 Page:673-681
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

López-Estévez S,Ferrer G,Torres-Torronteras J,Mansilla M J,Casacuberta-Serra S,Martorell L,Hirano M,Martí R,Barquinero J

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/gt201441.pdf

Reference31 articles.

1. Wang GP, Garrigue A, Ciuffi A, Ronen K, Leipzig J, Berry C et al. DNA bar coding and pyrosequencing to analyze adverse events in therapeutic gene transfer. Nucleic Acids Res 2008; 36: e49.

2. Lopez LC, Akman HO, Garcia-Cazorla A, Dorado B, Marti R, Nishino I et al. Unbalanced deoxynucleotide pools cause mitochondrial DNA instability in thymidine phosphorylase-deficient mice. Hum Mol Genet 2009; 18: 714–722.

3. Torres-Torronteras J, Gomez A, Eixarch H, Palenzuela L, Pizzorno G, Hirano M et al. Hematopoietic gene therapy restores thymidine phosphorylase activity in a cell culture and a murine model of MNGIE. Gene Therapy 2011; 18: 795–806.

4. Rivat C, Santilli G, Gaspar HB, Thrasher AJ . Gene therapy for primary immunodeficiencies. Hum Gene Ther 2012; 23: 668–675.

5. Simpson E, Scott D, James E, Lombardi G, Cwynarski K, Dazzi F et al. Minor H antigens: genes and peptides. Eur J Immunogenet 2001; 28: 505–513.

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