Genome-wide association studies: theoretical and practical concerns-Reference-Cited by-同舟云学术

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Genome-wide association studies: theoretical and practical concerns

Published:2005-02 Issue:2 Volume:6 Page:109-118
ISSN:1471-0056
Container-title:Nature Reviews Genetics
language:en
Short-container-title:Nat Rev Genet

Author:

Wang William Y. S.,Barratt Bryan J.,Clayton David G.,Todd John A.

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Genetics,Molecular Biology

Link

http://www.nature.com/articles/nrg1522.pdf

Reference104 articles.

1. Ioannidis, J. P., Trikalinos, T. A., Ntzani, E. E. & Contopoulos-Ioannidis, D. G. Genetic associations in large versus small studies: an empirical assessment. Lancet 361, 567–571 (2003).

2. Lohmueller, K. E., Pearce, C. L., Pike, M., Lander, E. S. & Hirschhorn, J. N. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nature Genet. 33, 177–182 (2003).

3. Hirschhorn, J. N. & Daly, M. J. Genome-wide association studies for common diseases and complex traits. Nature Rev. Genet. 6, 95–108 (2005). A review of the issues that are involved in the design of large-scale association mapping, including marker selection and sources of false-positive and false-negative results.

4. Livak, K. J., Marmaro, J. & Todd, J. A. Towards fully automated genome-wide polymorphism screening. Nature Genet. 9, 341–342 (1995).

5. Patil, N. et al. Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21. Science 294, 1719–1723 (2001).

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