Genomic imprinting effects on brain development and function
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Neuroscience
Link
http://www.nature.com/articles/nrn2235.pdf
Reference123 articles.
1. Reik, W. & Walter, J. Genomic imprinting: parental influence on the genome. Nature Rev. Genet. 2, 21–32 (2001).
2. Davies, W., Isles, A. R. & Wilkinson, L. S. Imprinted gene expression in the brain. Neurosci. Biobehav. Rev. 29, 421–430 (2005).
3. Fowden, A. L., Sibley, C., Reik, W. & Constancia, M. Imprinted genes, placental development and fetal growth. Horm. Res. 65 (Suppl. 3), 50–58 (2006).
4. Wilkins, J. F. & Haig, D. What good is genomic imprinting: the function of parent-specific gene expression. Nature Rev. Genet. 4, 359–368 (2003).
5. Barton, S. C., Surani, M. A. & Norris, M. L. Role of paternal and maternal genomes in mouse development. Nature 311, 374–376 (1984). Together with this reference 6, this study provided the first indication that both parental genomes are essential for normal development in mammals, suggesting that the maternal and paternal genomes are not functionally equivalent. It thus presaged the existence of imprinted genes.
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