QIAD assay for quantitating a compound’s efficacy in elimination of toxic Aβ oligomers-Reference-Cited by-同舟云学术

QIAD assay for quantitating a compound’s efficacy in elimination of toxic Aβ oligomers

Published:2015-09-23 Issue:1 Volume:5 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Brener Oleksandr,Dunkelmann Tina,Gremer Lothar,van Groen Thomas,Mirecka Ewa A.,Kadish Inga,Willuweit Antje,Kutzsche Janine,Jürgens Dagmar,Rudolph Stephan,Tusche Markus,Bongen Patrick,Pietruszka Jörg,Oesterhelt Filipp,Langen Karl-Josef,Demuth Hans-Ulrich,Janssen Arnold,Hoyer Wolfgang,Funke Susanne A.,Nagel-Steger Luitgard,Willbold Dieter

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep13222.pdf

Reference31 articles.

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2. Klein, W. L., Krafft, G. A. & Finch, C. E. Targeting small Abeta oligomers: the solution to an Alzheimer’s disease conundrum? Trends Neurosci 24, 219–224 (2001).

3. Finder, V. H. & Glockshuber, R. Amyloid-beta aggregation. Neurodegener Dis 4, 13–27, doi: 10.1159/000100355 (2007).

4. Rzepecki, P. et al. Prevention of Alzheimer’s Disease-associated Aβ Aggregation by Rationally Designed Nonpeptidic β-Sheet Ligands. Journal of Biological Chemistry 279, 47497–47505, 10.1074/jbc.M405914200 (2004).

5. Ward, R. V. et al. Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of beta-amyloid peptide. Biochem J 348 Pt 1, 137–144 (2000).

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