Structures of HIV-1 RT–DNA complexes before and after incorporation of the anti-AIDS drug tenofovir-Reference-Cited by-同舟云学术

Structures of HIV-1 RT–DNA complexes before and after incorporation of the anti-AIDS drug tenofovir

Published:2004-04-25 Issue:5 Volume:11 Page:469-474
ISSN:1545-9993
Container-title:Nature Structural & Molecular Biology
language:en
Short-container-title:Nat Struct Mol Biol

Author:

Tuske Steve,Sarafianos Stefan G,Clark Arthur D,Ding Jianping,Naeger Lisa K,White Kirsten L,Miller Michael D,Gibbs Craig S,Boyer Paul L,Clark Patrick,Wang Gang,Gaffney Barbara L,Jones Roger A,Jerina Donald M,Hughes Stephen H,Arnold Eddy

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Structural Biology

Link

http://www.nature.com/articles/nsmb760.pdf

Reference34 articles.

1. Huang, H., Chopra, R., Verdine, G.L. & Harrison, S.C. Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance. Science 282, 1669– 1675 (1998).

2. Sarafianos, S.G. et al. Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with β-branched amino acids. Proc. Natl. Acad. Sci. USA 96, 10027– 10032 (1999).

3. Gao, H.Q., Boyer, P.L., Sarafianos, S.G., Arnold, E. & Hughes, S.H. The role of steric hindrance in 3TC resistance of human immunodeficiency virus type-1 reverse transcriptase. J. Mol. Biol. 300, 403– 418 (2000).

4. Boyer, P.L. et al. YADD mutants of human immunodeficiency virus type 1 and Moloney murine leukemia virus reverse transcriptase are resistant to lamivudine triphosphate (3TCTP) in vitro . J. Virol. 75, 6321– 6328 (2001).

5. Arion, D., Kaushik, N., McCormick, S., Borkow, G. & Parniak, M.A. Phenotypic mechanism of HIV-1 resistance to 3_-azido-3_-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase. Biochemistry 37, 15908– 15917 (1998).

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