Abstract
AbstractBone tissue engineering is pivotal in facilitating bone reconstruction by promoting persistent angiogenesis and osteogenesis. Initially, the hot gel composite hydrogel scaffold technique was employed. However, to address various limitations, numerous gel structures have since been developed, including osteogenic gellan gels, semi-interpenetrating network hydrogels, photoinduced crosslinking methacrylate gels, and supramolecular hydrogels. This review examines the mechanisms, formation principles, and medical benefits of these gel structures. In addition, novel bioengineering techniques to regulate human bone growth are expected to emerge in the future. This work is expected to significantly expedite the advancement of hydrogel membranes in the field of bone repair.
Publisher
Springer Science and Business Media LLC
Reference168 articles.
1. Guo, X. Dong, X., Zou, G., Gao, H. & Zhai, W. Strong and tough fibrous hydrogels reinforced by multiscale hierarchical structures with multimechanisms. Sci. Adv. 9, eadf7075 (2023).
2. de Souza Balbinot, G. et al. Niobium-containing bioactive glasses modulate alkaline phosphatase activity during bone repair. J. Biomed. Mater. Res. 111, 1224 (2023).
3. Xu, T. et al. Accelerating the prediction and discovery of peptide hydrogels with human-in-the-loop. Nat. Commun. 14, 3880 (2023).
4. Sun, H. et al. Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair. Bioact. Mater. 24, 477 (2023).
5. Zhang, C. et al. Visual growth of nano-HOFs for low-power memristive spiking neuromorphic system. Nano Energy 109, 108274 (2023).
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