Synthesis of chiral piperidines from pyridinium salts via rhodium-catalysed transfer hydrogenation
Author:
Funder
Pfizer Inc. | Pfizer UK
University of Liverpool
Innovate UK
Publisher
Springer Science and Business Media LLC
Subject
Process Chemistry and Technology,Biochemistry,Bioengineering,Catalysis
Link
https://www.nature.com/articles/s41929-022-00857-5.pdf
Reference52 articles.
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3. Wang, D.-S., Chen, Q.-A., Lu, S.-M. & Zhou, Y.-G. Asymmetric hydrogenation of heteroarenes and arenes. Chem. Rev. 112, 2557–2590 (2012).
4. Cyrański, M. K. Energetic aspects of cyclic pi-electron delocalization: evaluation of the methods of estimating aromatic stabilization energies. Chem. Rev. 105, 3773–3811 (2005).
5. Raynor, S. A. et al. A one-step, enantioselective reduction of ethyl nicotinate to ethyl nipecotinate using a constrained, chiral, heterogeneous catalyst. Chem. Commun. 1925–1926 (2000).
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