A strategic Ser/Cys exchange in the catalytic triad unlocks an acyltransferase-mediated synthesis of thioesters and tertiary amides
Author:
Publisher
Springer Science and Business Media LLC
Subject
Process Chemistry and Technology,Biochemistry,Bioengineering,Catalysis
Link
http://www.nature.com/articles/s41929-020-00539-0.pdf
Reference38 articles.
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3. Jordan, A. & Sneddon, H. F. Development of a solvent–reagent selection guide for the formation of thioesters. Green Chem. 21, 1900–1905 (2019).
4. Petchey, M. R. & Grogan, G. Enzyme-catalysed synthesis of secondary and tertiary amides. Adv. Synth. Catal. 361, 3895–3914 (2019).
5. YI, C. L., Huang, Y. T. & Lee, C. F. Synthesis of thioesters through copper catalyzed coupling of aldehydes with thiols in water. Green Chem. 15, 2476–2484 (2013).
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