Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis
Author:
Publisher
Springer Science and Business Media LLC
Subject
Process Chemistry and Technology,Biochemistry,Bioengineering,Catalysis
Link
http://www.nature.com/articles/s41929-019-0394-4.pdf
Reference41 articles.
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3. Arnold, F. H. Directed evolution: bringing new chemistry to life. Angew. Chem. Int. Ed. 57, 4143–4148 (2018).
4. Acebes, S. et al. Rational enzyme engineering through biophysical and biochemical modeling. ACS Catal. 6, 1624–1629 (2016).
5. Seelig, B. & Szostak, J. W. Selection and evolution of enzymes from a partially randomized non-catalytic scaffold. Nature 448, 828–831 (2007).
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