Stereoselective construction of β-, γ- and δ-lactam rings via enzymatic C–H amidation-Reference-Cited by-同舟云学术

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Stereoselective construction of β-, γ- and δ-lactam rings via enzymatic C–H amidation

Published:2023-12-06 Issue:1 Volume:7 Page:65-76
ISSN:2520-1158
Container-title:Nature Catalysis
language:en
Short-container-title:Nat Catal

Author:

Roy Satyajit,Vargas David A.^ORCID,Ma Pengchen,Sengupta Arkajyoti^ORCID,Zhu Ledong,Houk K. N.^ORCID,Fasan Rudi^ORCID

Funder

U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences

NSF Graduate Research Fellowship program

National Natural Science Foundation of China

NSF | Directorate for Mathematical & Physical Sciences | Division of Mathematical Sciences

Publisher

Springer Science and Business Media LLC

Subject

Process Chemistry and Technology,Biochemistry,Bioengineering,Catalysis

Link

https://www.nature.com/articles/s41929-023-01068-2.pdf

Reference49 articles.

1. Guillemard, L., Kaplaneris, N., Ackermann, L. & Johansson, M. J. Late-stage C–H functionalization offers new opportunities in drug discovery. Nat. Rev. Chem. 5, 522–545 (2021).

2. Hong, B. K., Luo, T. P. & Lei, X. G. Late-stage diversification of natural products. ACS Cent. Sci. 6, 622–635 (2020).

3. Gutekunst, W. R. & Baran, P. S. C–H functionalization logic in total synthesis. Chem. Soc. Rev. 40, 1976–1991 (2011).

4. Wencel-Delord, J. & Glorius, F. C–H bond activation enables the rapid construction and late-stage diversification of functional molecules. Nat. Chem. 5, 369–375 (2013).

5. Upp, D. M. & Lewis, J. C. Selective C–H bond functionalization using repurposed or artificial metalloenzymes. Curr. Opin. Chem. Biol. 37, 48–55 (2017).

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