Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models-Reference-Cited by-同舟云学术

Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models

Published:2018-01-15 Issue:2 Volume:24 Page:194-202
ISSN:1078-8956
Container-title:Nature Medicine
language:en
Short-container-title:Nat Med

Author:

Schulte Michael L,Fu Allie,Zhao Ping,Li Jun,Geng Ling,Smith Shannon T,Kondo Jumpei,Coffey Robert J^ORCID,Johnson Marc O,Rathmell Jeffrey C,Sharick Joe T,Skala Melissa C,Smith Jarrod A,Berlin Jordan,Washington M Kay,Nickels Michael L,Manning H Charles

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Link

http://www.nature.com/articles/nm.4464.pdf

Reference42 articles.

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3. Hassanein, M. et al. SLC1A5 mediates glutamine transport required for lung cancer cell growth and survival. Clin. Cancer Res. 19, 560–570 (2013).

4. van Geldermalsen, M. et al. ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer. Oncogene 35, 3201–3208 (2016).

5. Schulte, M.L. et al. Non-invasive glutamine PET reflects pharmacological inhibition of BRAFV600Ein vivo. Mol. Imaging Biol. 19, 421–428 (2017).

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