Inhibition of DYRK1A and GSK3B induces human β-cell proliferation-Reference-Cited by-同舟云学术

Inhibition of DYRK1A and GSK3B induces human β-cell proliferation

Published:2015-10-26 Issue:1 Volume:6 Page:
ISSN:2041-1723
Container-title:Nature Communications
language:en
Short-container-title:Nat Commun

Author:

Shen Weijun,Taylor Brandon,Jin Qihui,Nguyen-Tran Van,Meeusen Shelly,Zhang You-Qing,Kamireddy Anwesh,Swafford Austin,Powers Andrew F.,Walker John,Lamb John,Bursalaya Badry,DiDonato Michael,Harb George,Qiu Minhua,Filippi Christophe M.,Deaton Lisa,Turk Carolina N.,Suarez-Pinzon Wilma L.,Liu Yahu,Hao Xueshi,Mo Tingting,Yan Shanshan,Li Jing,Herman Ann E.,Hering Bernhard J.,Wu Tom,Martin Seidel H.,McNamara Peter,Glynne Richard,Laffitte Bryan

Publisher

Springer Science and Business Media LLC

Subject

General Physics and Astronomy,General Biochemistry, Genetics and Molecular Biology,General Chemistry

Link

http://www.nature.com/articles/ncomms9372.pdf

Reference50 articles.

1. Matveyenko, A. V. & Butler, P. C. Relationship between beta-cell mass and diabetes onset. Diabetes Obes. Metab. 10, (Suppl 4): 23–31 (2008).

2. Butler, A. E. et al. Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 52, 102–110 (2003).

3. Stumvoll, M., Goldstein, B. J. & van Haeften, T. W. Type 2 diabetes: pathogenesis and treatment. Lancet 371, 2153–2156 (2008).

4. Schafer, S. A., Machicao, F., Fritsche, A., Haring, H. U. & Kantartzis, K. New type 2 diabetes risk genes provide new insights in insulin secretion mechanisms. Diabetes Res. Clin. Pract. 93, (Suppl 1): S9–S24 (2011).

5. Dor, Y., Brown, J., Martinez, O. I. & Melton, D. A. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429, 41–46 (2004).

Cited by 171 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, synthesis and evaluation of the first DYRK1A degrader for promoting the proliferation of pancreatic β-cells;Chinese Chemical Letters;2024-11

2. Dual role of neuroplastin in pancreatic β cells: Regulating insulin secretion and promoting islet inflammation;Proceedings of the National Academy of Sciences;2024-08-06

3. Harmine and exendin-4 combination therapy safely expands human β cell mass in vivo in a mouse xenograft system;Science Translational Medicine;2024-07-10

4. Zinc-chelating BET bromodomain inhibitors equally target islet endocrine cell types;American Journal of Physiology-Regulatory, Integrative and Comparative Physiology;2024-06-01

5. Select DYRK1A Inhibitors Enhance Both Proliferation and Differentiation in Human Pancreatic Beta Cells;2024-05-17