Upregulation of FOXM1 in a subset of relapsed myeloma results in poor outcome

Author:

Gu Chunyan,Holman Carol,Sompallae Ramakrishna,Jing Xuefang,Tomasson Michael,Hose Dirk,Seckinger Anja,Zhan Fenghuang,Tricot Guido,Goldschmidt Hartmut,Yang Ye,Janz SiegfriedORCID

Publisher

Springer Science and Business Media LLC

Subject

Oncology,Hematology

Reference15 articles.

1. Gu, C. et al. FOXM1 is a therapeutic target for high-risk multiple myeloma. Leukemia 30, 873–882 (2016).

2. Nandi, D., Cheema, P. S., Jaiswal, N., Nag, A. FoxM1: repurposing an oncogene as a biomarker. Semin. Cancer Biol. (2017) Pii: S1044-579X(17)30061-5.

3. Hose, D. et al. Proliferation is a central independent prognostic factor and target for personalized and risk-adapted treatment in multiple myeloma. Haematologica 96, 87–95 (2011).

4. Weinhold, N. et al. Clonal selection and double hit events involving tumor suppressor genes underlie relapse from chemotherapy: myeloma as a model. Blood 128, 1735–1744 (2016).

5. Fry, D. W. et al. Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts. Mol. Cancer Ther. 3, 1427–1438 (2004).

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