Consolidation with carfilzomib, lenalidomide, and dexamethasone (KRd) following ASCT results in high rates of minimal residual disease negativity and improves bone metabolism, in the absence of bisphosphonates, among newly diagnosed patients with multiple myeloma
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Hematology
Link
http://www.nature.com/articles/s41408-020-0297-2.pdf
Reference17 articles.
1. Ntanasis-Stathopoulos, I., Gavriatopoulou, M., Kastritis, E., Terpos, E. & Dimopoulos, M. A. Multiple myeloma: role of autologous transplantation. Cancer Treat Rev. 82, 101929 (2019).
2. Lehners, N. et al. Analysis of long-term survival in multiple myeloma after first-line autologous stem cell transplantation: impact of clinical risk factors and sustained response. Cancer Med. 7, 307–316 (2018).
3. Munshi, N. C. et al. Association of minimal residual disease with superior survival outcomes in patients with multiple myeloma: a meta-analysis. JAMA Oncol. 3, 28–35 (2017).
4. Terpos, E., Ntanasis-Stathopoulos, I. & Dimopoulos, M. A. Myeloma bone disease: from biology findings to treatment approaches. Blood 133, 1534–1539 (2019).
5. Landgren, O. et al. Carfilzomib with immunomodulatory drugs for the treatment of newly diagnosed multiple myeloma. Leukemia 33, 2127–2143 (2019).
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