Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology,General Medicine
Link
http://www.nature.com/articles/aps2010103.pdf
Reference68 articles.
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2. Farmer H, McCabe N, Lord CJ, Tutt AN, Johnson DA, Richardson TB, et al. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature 2005; 434: 917–21.
3. Rouleau M, Patel A, Hendzel MJ, Kaufmann SH, Poirier GG . PARP inhibition: PARP1 and beyond. Nat Rev Cancer 2010; 10: 293–301.
4. Schreiber V, Dantzer F, Ame JC, de Murcia G . Poly(ADP-ribose): novel functions for an old molecule. Nat Rev Mol Cell Biol 2006; 7: 517–28.
5. Ferraris DV . Evolution of Poly(ADP-ribose) Polymerase-1 (PARP-1) Inhibitors. From Concept to Clinic. J Med Chem 2010; 53: 4561–84.
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