Antiepileptic drugs reduce efficacy of methotrexate chemotherapy by downregulation of Reduced folate carrier transport activity
Author:
Publisher
Springer Science and Business Media LLC
Subject
Oncology,Cancer Research,Hematology
Link
http://www.nature.com/articles/leu20096.pdf
Reference56 articles.
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2. Relling MV, Pui CH, Sandlund JT, Rivera GK, Hancock ML, Boyett JM et al. Adverse effect of anticonvulsants on efficacy of chemotherapy for acute lymphoblastic leukaemia. Lancet 2000; 356: 285–290.
3. Riva M, Landonio G, Defanti CA, Siena S . The effect of anticonvulsant drugs on blood levels of methotrexate. J Neurooncol 2000; 48: 249–250.
4. Vecht CJ, Wagner GL, Wilms EB . Interactions between antiepileptic and chemotherapeutic drugs. Semin Oncol 2003; 30: 49–52.
5. Ochs JJ, Bowman WP, Pui CH, Abromowitch M, Mason C, Simone JV . Seizures in childhood lymphoblastic leukaemia patients. Lancet 1984; 2: 1422–1424.
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