Optimization of viral protein ratios for production of rAAV serotype 5 in the baculovirus system-Reference-Cited by-同舟云学术

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Optimization of viral protein ratios for production of rAAV serotype 5 in the baculovirus system

Published:2018-08-01 Issue:6 Volume:25 Page:415-424
ISSN:0969-7128
Container-title:Gene Therapy
language:en
Short-container-title:Gene Ther

Author:

Bosma Bas,du Plessis Francois,Ehlert Erich,Nijmeijer Bart,de Haan Martin,Petry Harald,Lubelski Jacek

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.nature.com/articles/s41434-018-0034-7.pdf

Reference25 articles.

1. van Oers MM. Opportunities and challenges for the baculovirus expression system. J Invertebr Pathol. 2011;107(Suppl):S3–15.

2. Urabe M, Ding C, Kotin RM. Insect cells as a factory to produce adeno-associated virus type 2 vectors. Hum Gene Ther. 2002;13:1935–43.

3. Trempe JP, Carter BJ. Alternate mRNA splicing is required for synthesis of adeno-associated virus VP1 capsid protein. J Virol. 1988;62:3356–63.

4. Cassinotti P, Weitz M, Tratschin JD. Organization of the adeno-associated virus (AAV) capsid gene: mapping of a minor spliced mRNA coding for virus capsid protein 1. Virology. 1988;167:176–84.

5. Smith RH, Levy JR, Kotin RM. A simplified baculovirus-AAV expression vector system coupled with one-step affinity purification yields high-titer rAAV stocks from insect cells. Mol Ther. 2009;17:1888–96.

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