Adeno-associated virus genome quantification with amplification-free CRISPR-Cas12a
Author:
Funder
National Institute for Innovation in Manufacturing Biopharmaceuticals
Publisher
Springer Science and Business Media LLC
Link
https://www.nature.com/articles/s41434-024-00449-x.pdf
Reference47 articles.
1. Rose JA, Hoggan MD, Shatkin AJ. Nucleic acid from an adeno-associated virus: chemical and physical studies. PNAS. 1966;56:86–92.
2. Naso MF. Adeno-Associated Virus (AAV) as a vector for gene therapy. BioDrugs. 2017;31:315–32.
3. Wang D, Tai PWL, Gao G. Adeno-associated virus vector as a platform for gene therapy delivery. Nat Rev Drug Discov. 2019;18:358–78.
4. Au HKE, Isalan M, Mielcarek M. Gene therapy advances: a meta-analysis of AAV usage in clinical settings. Front Med. 2022;8:1–14.
5. Srivastava A, Mallela KMG, Deorkar N, Brophy G. Manufacturing challenges and rational formulation development for AAV viral vectors. J Pharm Sci. 2021;110:2609–24.
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