Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation-Reference-Cited by-同舟云学术

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Small extracellular vesicle-mediated targeting of hypothalamic AMPKα1 corrects obesity through BAT activation

Published:2021-10 Issue:10 Volume:3 Page:1415-1431
ISSN:2522-5812
Container-title:Nature Metabolism
language:en
Short-container-title:Nat Metab

Author:

Milbank Edward,Dragano Nathalia R. V.^ORCID,González-García Ismael^ORCID,Garcia Marcos Rios,Rivas-Limeres Verónica,Perdomo Liliana,Hilairet Grégory,Ruiz-Pino Francisco,Mallegol Patricia,Morgan Donald A.,Iglesias-Rey Ramón,Contreras Cristina,Vergori Luisa,Cuñarro Juan,Porteiro Begoña,Gavaldà-Navarro Aleix^ORCID,Oelkrug Rebecca,Vidal Anxo,Roa Juan,Sobrino Tomás^ORCID,Villarroya Francesc^ORCID,Diéguez Carlos,Nogueiras Rubén^ORCID,García-Cáceres Cristina^ORCID,Tena-Sempere Manuel,Mittag Jens,Carmen Martínez M.^ORCID,Rahmouni Kamal,Andriantsitohaina Ramaroson^ORCID,López Miguel^ORCID

Funder

Deutsche Forschungsgemeinschaft

Ministerio de Economía y Competitividad

Department of Veterans Affairs | Office of Academic Affiliations, Department of Veterans Affairs

EC | Horizon 2020 Framework Programme

Consellería de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia

“la Caixa” Foundation

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Physiology (medical),Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

https://www.nature.com/articles/s42255-021-00467-8.pdf

Reference60 articles.

1. Clemmensen, C., Muller, T. D., Finan, B., Tschop, M. H. & DiMarchi, R. Current and emerging treatment options in diabetes care. Handb. Exp. Pharmacol. 233, 437–459 (2016).

2. Tschop, M. H. et al. Unimolecular polypharmacy for treatment of diabetes and obesity. Cell Metab. 24, 51–62 (2016).

3. López, M., Nogueiras, R., Tena-Sempere, M. & Dieguez, C. Hypothalamic AMPK: a canonical regulator of whole-body energy balance. Nat. Rev. Endocrinol. 12, 421–432 (2016).

4. Cui, H., López, M. & Rahmouni, K. The cellular and molecular bases of leptin and ghrelin resistance in obesity. Nat. Rev. Endocrinol. 13, 338–351 (2017).

5. Muller, T. D., Clemmensen, C., Finan, B., Dimarchi, R. D. & Tschop, M. H. Anti-obesity therapy: from rainbow pills to polyagonists. Pharmacol. Rev. 70, 712–746 (2018).

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