Metabolic enzyme LDHA activates Rac1 GTPase as a noncanonical mechanism to promote cancer-Reference-Cited by-同舟云学术

Metabolic enzyme LDHA activates Rac1 GTPase as a noncanonical mechanism to promote cancer

Published:2022-12-19 Issue:12 Volume:4 Page:1830-1846
ISSN:2522-5812
Container-title:Nature Metabolism
language:en
Short-container-title:Nat Metab

Author:

Liu Juan,Zhang Cen,Zhang Tianliang,Chang Chun-Yuan,Wang Jianming^ORCID,Bazile Ludvinna,Zhang Lanjing^ORCID,Haffty Bruce G.,Hu Wenwei^ORCID,Feng Zhaohui^ORCID

Funder

U.S. Department of Health & Human Services | NIH | National Cancer Institute

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Physiology (medical),Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

https://www.nature.com/articles/s42255-022-00708-4.pdf

Reference70 articles.

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3. Zhu, J. & Thompson, C. B. Metabolic regulation of cell growth and proliferation. Nat. Rev. Mol. Cell Biol. 20, 436–450 (2019).

4. Girgis, H. et al. Lactate dehydrogenase A is a potential prognostic marker in clear cell renal cell carcinoma. Mol. Cancer 13, 101 (2014).

5. Huang, X. et al. High expressions of LDHA and AMPK as prognostic biomarkers for breast cancer. Breast 30, 39–46 (2016).

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