Ammonia stimulates SCAP/Insig dissociation and SREBP-1 activation to promote lipogenesis and tumour growth-Reference-Cited by-同舟云学术

Ammonia stimulates SCAP/Insig dissociation and SREBP-1 activation to promote lipogenesis and tumour growth

Published:2022-05-09 Issue:5 Volume:4 Page:575-588
ISSN:2522-5812
Container-title:Nature Metabolism
language:en
Short-container-title:Nat Metab

Author:

Cheng Chunming^ORCID,Geng Feng,Li Zoe,Zhong Yaogang,Wang Huabao,Cheng Xiang^ORCID,Zhao Yue^ORCID,Mo Xiaokui^ORCID,Horbinski Craig^ORCID,Duan Wenrui,Chakravarti Arnab,Cheng Xiaolin,Guo Deliang^ORCID

Funder

U.S. Department of Health & Human Services | National Institutes of Health

U.S. Department of Health & Human Services | NIH | National Cancer Institute

U.S. Department of Health & Human Services | NIH | National Institute of Neurological Disorders and Stroke

American Cancer Society

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Physiology (medical),Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

https://www.nature.com/articles/s42255-022-00568-y.pdf

Reference70 articles.

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3. Cheng, X., Li, J. & Guo, D. SCAP/SREBPs are central players in lipid metabolism and novel metabolic targets in cancer therapy. Curr. Top. Med. Chem. 18, 484–493 (2018).

4. Nohturfft, A. & Zhang, S. C. Coordination of lipid metabolism in membrane biogenesis. Annu. Rev. Cell Dev. Biol. 25, 539–566 (2009).

5. Goldstein, J. L., DeBose-Boyd, R. A. & Brown, M. S. Protein sensors for membrane sterols. Cell 124, 35–46 (2006).

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