Complex regulatory processes control exercise adaptations of skeletal muscle
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Physiology (medical),Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
https://www.nature.com/articles/s42255-023-00894-9.pdf
Reference5 articles.
1. Furrer, R., Hawley, J. A. & Handschin, C. The molecular athlete: exercise physiology from mechanisms to medals. Physiol. Rev. 103, 1693–1787 (2023). A comprehensive review that summarizes the current knowledge of exercise adaptations, linking molecular mechanisms to cellular adaptations and training paradigms.
2. Pedersen, B. K. & Saltin, B. Exercise as medicine - evidence for prescribing exercise as therapy in 26 different chronic diseases. Scand. J. Med. Sci. Sports 25, 1–72 (2015). A review on the evidence of the efficacy of exercise to prevent and/or ameliorate several chronic diseases.
3. Seaborne, R. A. & Sharples, A. P. The interplay between exercise metabolism, epigenetics, and skeletal muscle remodeling. Exerc. Sport Sci. Rev. 48, 188–200 (2020). This review discusses the contemporary view of the molecular events that mediate training adaptation in skeletal muscle.
4. Handschin, C. Caloric restriction and exercise "mimetics'': ready for prime time. Pharmacol. Res. 103, 158–166 (2016). A review that outlines the potential and pitfalls of pharmacological modulation of mediators of muscle plasticity in exercise.
5. Sanford, J. A. et al. Molecular transducers of physical activity consortium (MoTrPAC): mapping the dynamic responses to exercise. Cell 181, 1464–1474 (2020). This review describes the NIH-funded MoTrPAC initiative, including current shortcomings in our understanding of exercise and how to close existing gaps in knowledge.
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