Interaction between hormone-sensitive lipase and ChREBP in fat cells controls insulin sensitivity
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cell Biology,Physiology (medical),Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
http://www.nature.com/articles/s42255-018-0007-6.pdf
Reference58 articles.
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2. Morley, T. S., Xia, J. Y. & Scherer, P. E. Selective enhancement of insulin sensitivity in the mature adipocyte is sufficient for systemic metabolic improvements. Nat. Commun. 6, 7906 (2015).
3. Shearin, A. L., Monks, B. R., Seale, P. & Birnbaum, M. J. Lack of AKT in adipocytes causes severe lipodystrophy. Mol. Metab. 5, 472–479 (2016).
4. Softic, S. et al. Lipodystrophy due to adipose tissue specific insulin receptor knockout results in progressive NAFLD. Diabetes 65, 2187–2200 (2016).
5. Rondinone, C. M. et al. Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus. Proc. Natl Acad. Sci. USA 94, 4171–4175 (1997).
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