CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels-Reference-Cited by-同舟云学术

CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels

Published:2020-11 Issue:11 Volume:2 Page:1284-1304
ISSN:2522-5812
Container-title:Nature Metabolism
language:en
Short-container-title:Nat Metab

Author:

Chini Claudia C. S.,Peclat Thais R.^ORCID,Warner Gina M.,Kashyap Sonu,Espindola-Netto Jair Machado^ORCID,de Oliveira Guilherme C.,Gomez Lilian S.^ORCID,Hogan Kelly A.,Tarragó Mariana G.,Puranik Amrutesh S.^ORCID,Agorrody Guillermo^ORCID,Thompson Katie L.,Dang Kevin,Clarke Starlynn,Childs Bennett G.^ORCID,Kanamori Karina S.,Witte Micaela A.,Vidal Paola,Kirkland Anna L.,De Cecco Marco,Chellappa Karthikeyani,McReynolds Melanie R.^ORCID,Jankowski Connor^ORCID,Tchkonia Tamara^ORCID,Kirkland James L.^ORCID,Sedivy John M.,van Deursen Jan M.,Baker Darren J.,van Schooten Wim,Rabinowitz Joshua D.^ORCID,Baur Joseph A.^ORCID,Chini Eduardo N.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Physiology (medical),Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://www.nature.com/articles/s42255-020-00298-z.pdf

Reference79 articles.

1. Hogan, K. A., Chini, C. C. S. & Chini, E. N. The multi-faceted ecto-enzyme CD38: roles in immunomodulation, cancer, aging and metabolic diseases. Front. Immunol. 10, https://doi.org/10.3389/fimmu.2019.01187 (2019).

2. Katsyuba, E., Romani, M., Hofer, D. & Auwerx, J. NAD+ homeostasis in health and disease. Nat. Metab. 2, 9–31 (2020).

3. Johnson, S. & Imai, S.-I. NAD+ biosynthesis, aging and disease. F1000Res 7, 132 (2018).

4. McReynolds, M. R., Chellappa, K. & Baur, J. A. Age-related NAD+ decline. Exp. Gerontol. 134, 110888 (2020).

5. Camacho-Pereira, J. et al. CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism. Cell Metab. 23, 1127–1139 (2016).

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