Designing screens: how to make your hits a hit
Author:
Publisher
Springer Science and Business Media LLC
Subject
Drug Discovery,Pharmacology,General Medicine
Link
http://www.nature.com/articles/nrd1063.pdf
Reference33 articles.
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3. Namchuk, M. Finding the molecules to fuel chemogenomics. Targets 1, 125–129 (2002).
4. Zhang, J. H., Chung, T. D. & Oldenburg, K. R. A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J. Biomol. Screen. 4, 27–32 (1999). Describes a widely used metric for defining the quality of high-throughput screening assays.
5. Miller, A. Discovery of cytokine mimics using cell-based systems. Drug Discov. Today 5, 77–83 (2000).
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