Recent insights how combined inhibition of immuno/proteasome subunits enables therapeutic efficacy
Author:
Funder
Deutsche Forschungsgemeinschaft
Else Kröner-Fresenius-Stiftung
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Genetics,Immunology
Link
https://www.nature.com/articles/s41435-020-00109-1.pdf
Reference121 articles.
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2. Schmidt C, Berger T, Groettrup M, Basler M. Immunoproteasome inhibition impairs T and B cell activation by restraining ERK signaling and proteostasis. Front Immunol. 2018;9:2386.
3. Basler M, Claus M, Klawitter M, Goebel H, Groettrup M. Immunoproteasome inhibition selectively kills human CD14(+) monocytes and as a result dampens IL-23 secretion. J Immunol. 2019;203:1776–85.
4. Vigneron N, Abi Habib J, Van den Eynde BJ. Learning from the proteasome how to fine-tune cancer immunotherapy. Trends Cancer. 2017;3:726–41.
5. Kisselev AF, van der Linden WA, Overkleeft HS. Proteasome inhibitors: an expanding army attacking a unique target. Chem Biol. 2012;19:99–115.
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